Customizable Clinical Panels

Add additional markers to immune profile specific cell types, targets, and pathways, relevant to your research

Each TokuProfile backbone panel was constructed based on extensive prior knowledge, input from our collaborative network, and years of experience over the course of multiple mass cytometry projects.

Importantly, each backbone panel includes at least 10 open channels to detect target-specific biomarkers and understand mechanism of action, dose selection, and drug pharmacodynamics.

Backbone panel

Identify biomarkers of response across the immune system with our pan-immune panel, or deep profile your T cell therapy product with our T cell panel

View panel backbone
group of hexagons icon

Pre-designed add-ons

Simplify panel customization with the option to add on one of our pre-designed 5-marker packages for whole blood at no additional cost.

View optional add-on packages
search icon

In-house and custom antibodies

Fill out the remaining open channels with one or more of the 130+ human antibodies we’ve tested in-house.

View in-house antibodies
Page Anchor: #human – Not Visible On Front

Expertly Designed Human Pan-Immune Panel Backbone (Customizable)

The TokuProfile Human Pan-Immune Panel Backbone includes:

  • Markers to identify every major immune cell population and subsets
  • Expression of key co-stimulatory and co-inhibitory molecules that regulate cell function
  • Markers of recent activation and effector function
  • Up to 10 open channels for customization included
Customize your panel

  • T cells

    CD3
    Total T cells
    CD4
    CD4+ T cells
    CD8a
    CD8+ T cells
    CD27
    Maturation
    CD45RA
    Naive/Memory
    CCR7 (CD197)
    Naive/Memory
    Foxp3
    Treg
    CD25
    Treg, activation
    CD127
    T cell subsets
    T-bet
    T cell subsets
    CD38
    Maturation
    HLA-DR
    Activation
    TCF1
    Stemness
    CD7
    T cell subsets
    CD56
    NKT, T cell subsets
    gdTCR
    gdT cells
    CTLA-4 (CD152)
    Checkpoint
    PD-1
    Checkpoint
    TIM-3
    Checkpoint
    TIGIT
    Checkpoint
    LAG3
    Checkpoint

  • B cells

    CD19
    Total B cells
    CD25
    Activation
    CD27
    Naive/Memory
    CD38
    Naive/Memory
    HLA-DR
    Antigen presentation

  • NK cells

    CD56
    NK cell subsets
    CD16
    NK cell subsets
    CD8a
    NK cell subsets
    CD7
    NK cell subsets
    CD38
    Activation
    T-bet
    Maturation

  • Myeloid cells

    CD11b
    Monocytes, macrophages
    CD11c
    Monocytes, macrophages, DCs
    CD14
    Monocyte subsets, Macrophages
    CD16
    Monocyte subsets
    CD33
    Total myeloid
    CD123
    pDC
    PD-L1
    Checkpoint ligand
    HLA-DR
    Antigen presentation

  • Granulocytes

    Whole blood only
    CD66b
    Granulocytes
    CD11b
    Neutrophils
    CD16
    Neutrophils
    CD123
    Basophils

  • General

    CD45
    Total immune cells
    KI67
    Proliferation
    CD61
    Platelets
    CD235ab
    Erythrocytes
    DNA
    Singlets
    Live/Dead
    Viability

  • 10 open channels for customization

Page Anchor: #add-on-packages – Not Visible On Front

Optional add-on package

Simplify your panel customization with our whole blood add-on package at no additional cost.

Our whole blood package is expertly designed to expand the human panel backbone to identify circulating granulocytes in whole blood.

  • Whole Blood add-on

    FcERI
    Basophils, Mast cells
    c-Kit
    Mast cells
    CD15
    Neutrophils
    Siglec-8
    Eosinophils
    LOX-1
    PMN-MDSCs

  • 5 remaining channels for customization

Page Anchor: #in-house-antibodies – Not Visible On Front

130+ antibodies tested in house

Choose from our list of over 130 antibody markers and clones tested and verified in-house. Don’t see your marker of interest on our list? Our team of expert scientists can work with you to add commercially-available or custom-target antibodies to your customized panel.

View full list
Page Anchor: #cytof-antibody-verification-process – Not Visible On Front
Technical Whitepaper

Technical Whitepaper

Teiko Bio’s Panel and Custom Antibody Verification Process

Fill out the form below to download the full technical whitepaper.