Publications

Immune features associated with clinical benefit and adverse events in response to immunotherapy in UC patients

Healy & Sweere et al. Cancer Res (2023)

Poster Highlights

To identify cell signatures associated with response and irAE development, we used mass cytometry to characterize the immune system in patients with urothelial cancer receiving aPD-1 therapy.

We found several immune features associated with survival, response to immunotherapy and presentation of adverse events

While some immune features were only associated with response, others were also associated with irAE.

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Reference citation: Healy CP, Sweere JM, Liang SI, Sigal N, Enrico E, Cheng L, Lucas A, Thompson MA, Da Silva DM, Jarrell JA, Srinivasan R, Spitzer MH, Nguyen N, Spencer CN. Immune features of irAEs and aPD1 response in urothelial cancer patients of the RADIOHEAD study, as detected in blood by mass cytometry immune profiling. 2023. Cancer Res 83 (7_Supplement): 2138. doi: 10.1158/1538-7445.AM2023-2138

White background with black and red text in the middle surrounded by squares of abstract red paint splotches. The title reads "Teiko.bio Peripheral immune Monitoring" and the subtitle reads "What looking beyond the tumor microenvironment taught us about immunotherapy."

What looking beyond the tumor microenvironment has taught us about immunotherapy

Dr. Jolien Sweere walks us through scientific publications showing that immune responses outside the tumor are necessary for effective immunotherapy.

Customer Spotlight: Shernan Holtan, MD

Dr. Shernan Holtan discusses her research into a pregnancy hormone that may hold the key to treating life-threatening graft-vs-host diseases and how Teiko helped her overcome the barriers to high-dimensional immune profiling.

Five things to look for in an immune profiling partner

Make the most of your time and resources by choosing an immune profiling partner who can advance your oncology, autoimmune, or infectious disease pipelines. Here are five things to look for when evaluating an immune profiling partner.

Poster Highlights

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What looking beyond the tumor microenvironment has taught us about immunotherapy

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