Category: Blood Collection

Rapid Onsite Fixation of Human Whole Blood Samples with Teiko’s Two-Step TokuKit for Clinical Trials

Rapid Onsite Fixation of Human Whole Blood Samples with Teiko’s TokuKit for Clinical TrialsDownload

About the Webinar

In this live webinar, Ramji Srinivasan, Cofounder and CEO, and Kristina Magee, Associate Director of Lab Operations, will guide you through a full demo of the TokuKit, covering ever step from blood draw to kit processing and storage at -80°C. The TokuKit is designed for collection, fixation, and long-term preservation of whole blood samples, for cytometry analysis of longitudinal patient samples from multi-site clinical trials.

About the Speakers

Before Teiko, Ramji was Cofounder, CEO and Chairman of Counsyl, a women’s health genetic screening laboratory. Counsyl screened over 1M prospective parents, mothers-to-be and women at risk of hereditary cancer. In 2018, Counsyl was acquired by Myriad Genetics, Inc for $375M in cash and stock.

Ramji earned a B.S. in computer science and an M.S. in financial mathematics, both from Stanford University. Ramji also attended Stanford’s Graduate School of Business before dropping out to start Counsyl.

Prior to Teiko, Kristina Magee completed her MD as well as PhD in Cell Biology at the University of Bern, Switzerland. There, she investigated metabolic targets for the use in AML differentiation therapies. Following this, she held a role as a Postdoctoral Fellow at the University of Utah before joining Teiko in early 2024.

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Whole Blood or PBMCs for immune profiling?

Whole Blood or PBMCs for Immune ProfilingDownload

About the Webinar

In this technical webinar, Jolien Sweere, PhD, discusses data from a technical validation experiment performed by Teiko Bio showing how mass cytometry immune profiling data from whole blood compares to data from PBMCs.

Technical validation slides available here.

About the Speaker

Jolien Sweere, PhD completed her doctoral training in Immunology at Stanford University in the laboratory of Paul Bollyky. During her PhD, she found that a type of temperate filamentous bacteriophage that infects Pseudomonas aeruginosa is associated with chronic human wound infections. Her work was published in Science in 2019.

After completing her PhD, Jolien worked as a Life Sciences commercial strategy consultant at Charles River Associates in San Francisco. She joined Teiko Bio in 2022 as a Senior Scientist, Medical Strategy.

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Illustration. In the center is a grey mass labeled "tumor" under a magnifying glass. Inside the tumor are three grey cells all with "zzz" above them. Outside the magnifying glass (and therefore outside the tumor) in the four corners are different depictions. Top left shows three red cells and is labeled "novel T cell clones". Top right shows a lymph node with red T cell zones and the words "LN trafficking required". Bottom right shows two red T cells in a blood vessel labeled "LAG-3 and CD8+" with the words "peripheral biomarkers". Bottom left shows a spleen with the same grey, sleeping T cells. There's a red lightning bolt and the words "impaired systemic immune response in cancer".

Peripheral blood analysis is key to developing effective cancer immunotherapies

Although most research focuses on tumor-killing immune cells at the site of the tumor, new research increasingly demonstrates the value of studying circulating immune cells in peripheral blood to identify new therapeutic targets to enhance tumor-killing immune responses. We highlight recent publications with peripheral blood biomarkers and discuss recommendations for how to incorporate peripheral blood immune profiling into your drug development pipeline.